microsatelliteinstabilitycoloncancer

由 CR Boland 著作 · 2010 · 被引用 2463 次 — Microsatellite instability (MSI) is a hypermutable phenotype caused by the loss of DNA mismatch repair activity. MSI is detected in about 15% of all ...

由 E Vilar 著作 · 2010 · 被引用 1080 次 — Microsatellite instability (MSI) is a frequent molecular phenomenon of colorectal cancer and is associated with deficient DNA mismatch ...

2023年3月6日 — It occurs at the highest rate in colon cancers, but still only occurs about 15% of the time. For all other cancer types, it's much less common, ...

2022年6月27日 — Microsatellite instability (MSI) is one of the hallmarks of a distinct subtype of colorectal cancer (CRC). Not only is it the diagnostic clue ...

由 F Battaglin 著作 · 被引用 193 次 — Abstract: Microsatellite instability (MSI) is a key biomarker in colorectal cancer (CRC), with crucial diagnostic, prognostic, and predictive implications.

由 K Li 著作 · 2020 · 被引用 348 次 — MSI is closely related to colorectal cancer (CRC), and some studies have found MS loci related to CRC. Saeterdal et al. [36] clarified that ...

由 S Kang 著作 · 2018 · 被引用 113 次 — The colorectal cancer (CRC) patients with microsatellite instability (MSI) have distinct clinicopathological characteristics consisting of factors ...

由 J Alexander 著作 · 2001 · 被引用 613 次 — Cancer with high levels of microsatellite instability (MSI-H) is the hallmark of hereditary nonpolyposis colorectal cancer syndrome, and MSI-H occurs in ...

MSI testing looks at the length of certain DNA microsatellites from the tumor sample to see if they have gotten longer or shorter as a measure of instability.